Axis Labs Creatine Ethyl Ester 10% Free, 360ct + 36 free ct

Creatine Ethyl Ester - Ester-Sorb™ Technology

Significant Absorption Means Impressive Results  
Axis Labs® has just exhausted the competition with our Creatine Ethyl Ester HCl. Creatine Ethyl Ester HCL is an exceptionally soluble creatine resulting in advanced absorption, increased bioavailability, and stability.  

The ethyl ester in Creatine Ethyl Ester HCL makes the molecule more lipid soluble and able to passively diffuse through cell membranes rapidly. This method of creatine delivery bypasses the creatine transporter on cell membranes and it allows creatine levels inside muscle cells to increase very rapidly and to higher levels than are possible with regular creatine monohydrate (see figure 1).  

Creatine Ethyl Ester HCl Highlights:
• Dramatically stronger than other forms of creatine
• Huge gains in lean mass through increased protein synthesis
• Directly penetrates the muscle cell
• Smaller dose that provides more results than regular creatine monohydrate
• Rapid results, feel the power in the first serving
• No loading, bloating, cramping or dehydration
• No need to cycle off  

Traditional Creatine Use  
Creatine is by far, one of the best discoveries that has ever hit the bodybuilding/fitness world. Creatine is a compound which is made in the body from the amino acids glycine and arginine, and is derived from the diet through meat and animal products. In the body, creatine is changed into a molecule called phosphocreatine which serves as a storage reservoir for regenerating ATP. ATP is the chemical source of energy for muscle contraction and quick energy. Phosphocreatine is an important source of ATP energy in muscle tissue and studies have shown that creatine can increase the performance of athletes in activities that require quick bursts of energy, such as sprinting and weight lifting.  

Creatine supplementation combined with strength training has been shown to cause dramatic improvements in muscle hypertrophy (size) and strength through cell volumization and increased protein synthesis. Cell volumization is an increase in muscle volume (size) caused when water follows creatine into our muscles. Cell volumization can increase strength by increasing the amount of force a muscle can contract with. There is also research that indicates that cell volumization and creatine supplementation can signal muscle cells to grown and increase protein synthesis, while preventing protein breakdown.  

Creatine monohydrate has proven effective in increasing muscle mass, strength and all around athletic performance and long-term clinical studies have also shown that creatine monohydrate is safe for use by people without medical conditions. However, creatine supplements are only as effective as their transport system.  

Where Regular Creatine is Lacking
Traditionally, creatine monohydrate has been taken with large amounts of carbohydrates and sodium to help shuttle the creatine into muscle cells. This is due to the relatively poor absorption rate of creatine without sugar and sodium. A loading phase of several days was necessary with traditional creatine monohydrate in an attempt to saturate muscle cells. Unfortunately the loading of creatine monohydrate along with high doses of sugar and salt can lead to bloating, cramping and dehydration.  

Increased Bioavailability and Effectiveness
Instead of saturating your system with creatine, sugar, and salt hoping for absorption, Creatine Ethyl Ester HCL directly penetrates the muscle cell resulting in dramatically more functional creatine per dose. This means no more loading, bloating, cramping or dehydration. Most users notice a difference in their first dose. Now you can have all the benefits of creatine supplementation without any of the side effects. Demand more from your creatine. Demand Axis Labs® Creatine Ethyl Ester. Hold on tight! You’re in for a ride…
 

Other Ingredients: Gelatin, Magnesium stearate.

Store in a cool dry place. Protect from heat, light and moisture.

Suggested Use: As a dietary supplement, take 2-4 capsules twice daily.

Workout days: Take 2-4 capsules with 16oz of water 15-30 minutes before workout. Take another 2-4 capsules with 16oz of water 15-30 minutes after workout.

Non workout days: Take 2-4 capsules with 16oz of water with first meal. Take another 2-4 capsules with 16oz of water with meal 4-6 hours later.

WARNING: KEEP OUT OF REACH OF CHILDREN. This product is not intended for anyone under the age of 18. Consult your physician before using this or any dietary supplement. Do not take this product if you have any medical conditions and/or are taking any prescription medication(s). Discontinue use if experiencing any adverse side effects.

*These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

Anomasiri, W., S. Sanguanrungsirikul, et al. 2004. Low dose creatine supplementation enhances sprint phase of 400 meters swimming performance. J Med Assoc Thai 87 Suppl 2: S228-32.

Brudnak, M. A. 2004. Creatine: are the benefits worth the risk? Toxicol Lett 150(1): 123-30.

Dempsey, R. L., M. F. Mazzone, et al. 2002. Does oral creatine supplementation improve strength? A meta-analysis. J Fam Pract 51(11): 945-51.

Falk, D. J., K. A. Heelan, et al. 2003. Effects of effervescent creatine, ribose, and glutamine supplementation on muscular strength, muscular endurance, and body composition. J Strength Cond Res 17(4): 810-6.

Feldman, E. B. 1999. Creatine: a dietary supplement and ergogenic aid. Nutr Rev 57(2): 45-50.

Froiland, K., W. Koszewski, et al. 2004. Nutritional supplement use among college athletes and their sources of information. Int J Sport Nutr Exerc Metab 14(1): 104-20.

Greenwood, M., J. Farris, et al. 2000. Creatine supplementation patterns and perceived effects in select division I collegiate athletes. Clin J Sport Med 10(3): 191-4.

Hoffman, J. R., J. R. Stout, et al. 2005. Effect of low-dose, short-duration creatine supplementation on anaerobic exercise performance. J Strength Cond Res 19(2): 260-4.

Huang, S. H., K. Johnson, et al. 2006. The use of dietary supplements and medications by Canadian athletes at the Atlanta and Sydney Olympic Games. Clin J Sport Med 16(1): 27-33.

Javierre, C., J. R. Barbany, et al. 2004. Creatine supplementation and performance in 6 consecutive 60 meter sprints. J Physiol Biochem 60(4): 265-71.

Kocak, S. and U. Karli. 2003. Effects of high dose oral creatine supplementation on anaerobic capacity of elite wrestlers. J Sports Med Phys Fitness 43(4): 488-92.

Kraemer, W. J. and J. S. Volek. 1999. Creatine supplementation. Its role in human performance. Clin Sports Med 18(3): 651-66, ix.

Kreider, R. B. 2003. Effects of creatine supplementation on performance and training adaptations. Mol Cell Biochem 244(1-2): 89-94.

LaBotz, M. and B. W. Smith. 1999. Creatine supplement use in an NCAA Division I athletic program. Clin J Sport Med 9(3): 167-9.

Lunardi, G., A. Parodi, et al. 2006. The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds. Neuroscience 142(4): 991-7.

McGuine, T. A., J. C. Sullivan, et al. 2002. Creatine supplementation in Wisconsin high school athletes. Wmj 101(2): 25-30.

McGuine, T. A., J. C. Sullivan, et al. 2001. Creatine supplementation in high school football players. Clin J Sport Med 11(4): 247-53.

Mendes, R. R., I. Pires, et al. 2004. Effects of creatine supplementation on the performance and body composition of competitive swimmers. J Nutr Biochem 15(8): 473-8.

Mendes, R. R. and J. Tirapegui. 2002. [Creatine: the nutritional supplement for exercise - current concepts]. Arch Latinoam Nutr 52(2): 117-27.

Metzl, J. D., E. Small, et al. 2001. Creatine use among young athletes. Pediatrics 108(2): 421-5.

Morrison, L. J., F. Gizis, et al. 2004. Prevalent use of dietary supplements among people who exercise at a commercial gym. Int J Sport Nutr Exerc Metab 14(4): 481-92.

Ostojic, S. M. 2004. Creatine supplementation in young soccer players. Int J Sport Nutr Exerc Metab 14(1): 95-103.

Poortmans, J. R. and M. Francaux. 2000. Adverse effects of creatine supplementation: fact or fiction? Sports Med 30(3): 155-70.

Rawson, E. S. and J. S. Volek. 2003. Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance. J Strength Cond Res 17(4): 822-31.

Silber, M. L. 1999. Scientific facts behind creatine monohydrate as sport nutrition supplement. J Sports Med Phys Fitness 39(3): 179-88.

Tarnopolsky, M. A., G. Parise, et al. 2001. Creatine-dextrose and protein-dextrose induce similar strength gains during training. Med Sci Sports Exerc 33(12): 2044-52.

Volek, J. S., N. D. Duncan, et al. 2000. No effect of heavy resistance training and creatine supplementation on blood lipids. Int J Sport Nutr Exerc Metab 10(2): 144-56.